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Michael Samuels, M.D.

General Information

Michael  Samuels, M.D.


  • Fax: 305-689-4451


  • Radiation Oncology



Clinical Areas

Radiation therapy of cancers of the head/neck and lung.


  • American Board of Radiology-Radiation Oncology


  • Associate Professor
  • Medical Director, UM/Sylvester Clinical Research Services

Research Interests

Toxicity reduction in the treatment of head/neck cancers

Functional rehabilitation after radiation therapy for head/neck cancers

DNA analysis of human papillomavirus-associated oropharynx cancers

Use of novel radiosensitizing compounds in the treatment of head and neck cancers

Use of immunotherapy for treatment of advanced squamous skin cancers


Elected to Fellowship with the American College of Radiology (FACR)
Recipient of the ASCO Clinical Trials Participation Award for the 2005 Mt. Sinai CCOP
Merck Award for medical scholarship
Elected to Alpha Omega Alpha Honor Medical Society (junior year)
Graduated Yale Magna Cum Laude, with Distinction in English


1993 Radiation Oncology-Permanent Certification
American Board of Radiology
1992 Chief Resident in Therapeutic Radiology
Yale-New Haven Hospital
1992 Resident in Therapeutic Radiology
Yale University/New Haven Hospital
1989 Intern
Boston University School of Medicine
1988 M.D
Tufts University School of Medicine
1984 B.A English
Yale University


Dr. Samuels received his medical degree from Tufts University in 1988 and completed his training in Therapeutic Radiology at Yale University in 1992. He then spent 8 years on the faculty of the Case Western Reserve School of Medicine in Cleveland, serving as Clinical Director of Radiation Oncology from 1998 to 2000 and leading the head and neck radiation oncology service. That year, he left Cleveland to practice in Miami at Mt. Sinai Medical Center, a community teaching hospital where he served as department Vice Chairman. In 2010, he joined the University of Miami Sylvester Cancer Center as Associate Professor of Clinical Radiation Oncology and director of the head/neck cancer radiation oncology service.

Dr. Samuels serves as Medical Director for the Sylvester Cancer Center Clinical Research Services (CRS), with over 100 employees and tasked with providing support for all cancer center interventional and many non-interventional clinical trials. Since assuming this position in 2011, the office has grown from approximately 20 staff members, with trial enrollment increasing approximately 8-fold over this time period.

Dr. Samuels’ clinical interests include the treatment of cancers of the head and neck and lung. His research interests are varied. They include serving as Principal Investigator of a translational research team investigating key DNA characteristics of human papillomavirus-associated oropharynx cancers. He has a long-standing interest in toxicity reduction for patients treated with radiotherapy or chemoradiotherapy for cancers of the head and neck, including techniques to reduce oral mucositis and carotid injury. He serves as national Lead Investigator on a phase I trial using a novel radiosensitizing compound in treatment of head/neck cancers. He also serves as national Radiation Oncology Principal Investigator on a National Cancer Institute trial exploring the use of immunotherapy to treat advanced squamous skin cancers of the head/neck region.

Dr. Samuels has national committee positions with NRG Oncology and the American Society for Radiation Oncology (ASTRO). In 2010, he was honored as a Fellow of the American College of Radiology. 

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